Abstract
Posttraumatic stress disorder (PTSD) is a highly prevalent disorder that is often linked to addictions due to common links in childhood trauma and efforts at self-medication. Treatments for PTSD including medications have limitations due to side effects and imperfect efficacy. Vagus nerve stimulation (VNS) is a non-pharmacological alternative approach that targets the excessive sympathetic and inflammatory conditions that characterize the neurobiology of the disorder. These properties of VNS also lend themselves to the treatment of addictions, such as with opioid withdrawal. This paper provides an overview of VNS for stress-related psychiatric disorders and addictions with a focus on new non-invasive forms of VNS that have the potential to have widespread application to psychiatry due to lower cost and increased convenience.
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